Article
The autoregulatory HspR repressor protein governs chaperone gene transcription in <i>Helicobacter pylori</i>
1 Nov 1999
Abstract excerpt
In the present study, we provide evidence that the groESL, hrcA-grpE-dnaK and cbpA-hspR-orf operons encoding the major chaperones of the human gastric pathogen Helicobacter pylori are transcribed by the vegetative sigma factor sigma80 and are regulated negatively by the transcriptional repressor HspR. In vitro studies with purified recombinant HspR protein established that the protein represses transcription by...
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