Transcriptional analysis of the <i>Streptococcus mutans hrcA</i>, <i>grpE</i> and <i>dnaK</i> genes and regulation of expression in response to heat shock and environmental acidification

Abstract excerpt

The dental pathogen Streptococcus mutans persists and causes diseases in highly dynamic environments and gains a selective ecological advantage in environmental conditions that frequently exceed the limits for growth of the organism, particularly with regard to environmental pH. The goal of this study was to begin a molecular genetic analysis of a major stress protein, DnaK/Hsp70, to begin to understand how...

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