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Article

Filamentous growth of Candida albicans in response to physical environmental cues and its regulation by the unique CZF1 gene.

Molecular microbiology - 1 Nov 1999

Brown D H, Giusani A D, Chen X, Kumamoto C A

Abstract excerpt

Hyphal growth in the opportunistic fungal pathogen Candida albicans is believed to contribute to the virulence of the organism by promoting penetration of fungal cells into host tissue. In this study, stimulation of hyphal growth by a feature of the physical environment was demonstrated. Specifically, growth of cells embedded within a matrix promoted the formation of hyphae. The CZF1 gene, encoding a putative...

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PMID: 10564506
DOI: 10.1046/j.1365-2958.1999.01619.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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