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Article

Functional consequences of mutations in the conserved 'signature sequence' of the ATP-binding-cassette protein MalK.

European journal of biochemistry - 1 Dec 1999

Schmees G, Stein A, Hunke S, Landmesser H, Schneider E

Abstract excerpt

The binding-protein-dependent maltose-transport system of enterobacteria, a member of the ATP-binding-cassette (ABC) transporter superfamily, is composed of two integral membrane proteins, MalF and MalG, and two copies of an ATPase subunit, MalK, which hydrolyze ATP, thus energizing the translocation process. Isolated MalK displays spontaneous ATPase activity, whereas in the assembled MalFGK2 complex,...

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Identifiers

PMID: 10561582
DOI: 10.1046/j.1432-1327.1999.00871.x

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Functional consequences of mutations in the conserved 'signature sequence' of the ATP-binding-cassette protein MalK.PMID 10561582Read ↗

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