Article
Subunit interactions in ABC transporters: a conserved sequence in hydrophobic membrane proteins of periplasmic permeases defines an important site of interaction with the ATPase subunits.
The EMBO journal - 2 Jun 1997
Mourez M, Hofnung M, Dassa E
Abstract excerpt
The cytoplasmic membrane proteins of bacterial binding protein-dependent transporters belong to the superfamily of ABC transporters. The hydrophobic proteins display a conserved, at least 20 amino acid EAA---G---------I-LP region exposed in the cytosol, the EAA region. We mutagenized the EAA regi...
Topics
- ATP-Binding Cassette Transporters
- Adenosine Triphosphatases
- Bacterial Proteins
- Biological Transport
- Carrier Proteins
- Cell Compartmentation
- Cell Membrane
- Conserved Sequence
- Cytoplasm
- Escherichia coli
- Escherichia coli Proteins
- Maltose
- Maltose-Binding Proteins
- Monosaccharide Transport Proteins