Article
Participation of Bir1p, a member of the inhibitor of apoptosis family, in yeast chromosome segregation events.
Proceedings of the National Academy of Sciences of the United States of America - 9 Nov 1999
Yoon H J, Carbon J
Abstract excerpt
Yeast two-hybrid and genetic interaction screens indicate that Bir1p, a yeast protein containing phylogenetically conserved antiapoptotic repeat domains called baculovirus inhibitor of apoptosis repeats (BIRs), is involved in chromosome segregation events. In the two-hybrid screen, Bir1p specifically interacts with Ndc10p, an essential component of the yeast kinetochore. Although Bir1p carries two BIR motifs in...
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