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Article

Deletogenic activity of 1,2:7,8-diepoxyoctane in the Salmonella typhimurium tester strain TA102.

Mutation research - 1 Sept 1999

Picada J N, Khromov-Borisov N N, Henriques J A

Abstract excerpt

1,2:7,8-Diepoxyoctane (DEO), whose deletogenic activity was first demonstrated in ad-3 system of Neurospora crassa and then in different species, has been tested in Salmonella typhimurium tester strain TA102 (hisG428(Ochre)). It was confirmed that it is a direct acting mutagen and was found that its activity is stimulated with the S9 mix. Obtained His(+) revertants were screened on their response to the histidine...

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PMID: 10556620
DOI: 10.1016/s1383-5742(99)00082-4

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