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Article

Substitution with selenomethionine can enhance the stability of methionine-rich proteins.

Journal of molecular biology - 19 Nov 1999

Gassner N C, Baase W A, Hausrath A C, Matthews B W

Abstract excerpt

The availability of a series of phage T4 lysozymes with up to 14 methionine residues incorporated within the protein has made it possible to systematically compare the effect on protein stability of selenomethionine relative to methionine. Wild-type lysozyme contains two fully buried methionine residues plus three more on the surface. The substitution of these methionine residues with selenomethionine slightly...

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Identifiers

PMID: 10556025
DOI: 10.1006/jmbi.1999.3220

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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