Article
The relative contributions of recombination and mutation to the divergence of clones of Neisseria meningitidis.
Molecular biology and evolution - 1 Nov 1999
Feil E J, Maiden M C, Achtman M, Spratt B G
Abstract excerpt
Multilocus sequence typing (MLST) is a recently developed nucleotide sequence-based method for the definitive assignment of isolates within bacterial populations to specific clones. MLST uses the same principles as multilocus enzyme electrophoresis and provides data that can be used to investigate aspects of the population genetics and evolution of bacterial species. We used an MLST data set consisting of the...
Topics
- Alleles
- Base Sequence
- DNA, Bacterial
- Genetic Variation
- Molecular Sequence Data
- Neisseria meningitidis
- Point Mutation
- Polymorphism, Genetic
- Recombination, Genetic
- Sequence Homology, Nucleic Acid