Article
The influence of mutation, recombination, population history, and selection on patterns of genetic diversity in Neisseria meningitidis.
Molecular biology and evolution - 1 Mar 2005
Jolley K A, Wilson D J, Kriz P, McVean G, Maiden M C J
Abstract excerpt
Patterns of genetic diversity within populations of human pathogens, shaped by the ecology of host-microbe interactions, contain important information about the epidemiological history of infectious disease. Exploiting this information, however, requires a systematic approach that distinguishes the genetic signal generated by epidemiological processes from the effects of other forces, such as recombination,...
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