Article
Homologous recombination drives both sequence diversity and gene content variation in Neisseria meningitidis.
Genome biology and evolution - 1 Jan 2013
Kong Ying, Ma Jennifer H, Warren Keisha, Tsang Raymond S W, Low Donald E, Jamieson Frances B, Alexander David C, Hao Weilong
Abstract excerpt
The study of genetic and phenotypic variation is fundamental for understanding the dynamics of bacterial genome evolution and untangling the evolution and epidemiology of bacterial pathogens. Neisseria meningitidis (Nm) is among the most intriguing bacterial pathogens in genomic studies due to its dynamic population structure and complex forms of pathogenicity. Extensive genomic variation within identical clonal...
Topics
- DNA, Bacterial
- Evolution, Molecular
- Genetic Variation
- Genome, Bacterial
- Homologous Recombination
- Humans
- Molecular Sequence Data
- Neisseria meningitidis
- Phylogeny