Article
Age at time of hepatitis Be antibody seroconversion in childhood chronic hepatitis B infection and mutant viral strain detection rates.
Journal of pediatric gastroenterology and nutrition - 1 Nov 1999
Ando T, Sugiyama K, Goto K, Miyake Y, Li R, Kawabe Y, Wada Y
Abstract excerpt
BACKGROUND: Investigations of adult patients have demonstrated that with seroconversion, changes occur from wild-type strains of the infecting virus to mutant strains. However, to date, there have been few reports and insufficient investigation of this issue in children. METHODS: The presence or absence of nucleotide base and amino acid sequence mutations in a portion of the X region containing the core promoter...
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