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Article

Progestin regulation in tumor growth of female genital tract cancers.

Oncology - 1 Oct 1999

Fujimoto J, Sakaguchi H, Misao R, Hirose R, Wen H, Tamaya T

Abstract excerpt

The irregular response to progestins directly in tumor growth might be caused by dominant negative progesterone receptor (PR) mutants and the damage to PR-A expression. Progestin treatment as an anti-angiogenic therapy would be less effective in the PR-mutated tumors. Therefore, various anti-angiogenic inhibitors must be used in progestin-refractory and progestin-dependent tumors.

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Source

Identifiers

PMID: 10545804
DOI: 10.1159/000055276

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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