Article
The progesterone receptor gene polymorphism, PROGINS, may be a factor related to the development of uterine fibroids.
Fertility and sterility - 1 May 2007
Gomes Mariano Tamura Vieira, Castro Rodrigo de Aquino, Villanova Fabiola Elizabeth, da Silva Ismael Dale Cotrim Guerreiro, Baracat Edmund Chada, de Lima Geraldo Rodrigues, Girão Manoel João Batista Castello
Abstract excerpt
OBJECTIVE: To assess the possible association between the polymorphic allele of the progesterone receptor gene, named PROGINS, and uterine leiomyomas. DESIGN: Case-control study. SETTING: Department of Gynecology. Teaching hospital. PATIENT(S): One hundred twenty-two premenopausal women with fibroids and 125 postmenopausal controls not presenting the disease. INTERVENTION(S): The subjects were classified as White...
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