Article
No association between androgen or vitamin D receptor gene polymorphisms and risk of breast cancer.
Carcinogenesis - 1 Nov 1999
Dunning A M, McBride S, Gregory J, Durocher F, Foster N A, Healey C S, Smith N, Pharoah P D, Luben R N, Easton D F, Ponder B A
Abstract excerpt
Endogenous hormone exposure is known to alter breast cancer susceptibility and genes responsive to such hormones are plausible candidates for predisposition genes. We have examined polymorphisms in genes for two members of the nuclear receptor superfamily which are expressed in breast tissue and known to moderate rates of cell proliferation in a case-control association study: the androgen receptor (AR) and the...
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