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Article

Expression of the BLM gene in human haematopoietic cells.

Clinical and experimental immunology - 1 Nov 1999

Kaneko H, Matsui E, Fukao T, Kasahara K, Morimoto W, Kondo N

Abstract excerpt

Bloom's syndrome (BS) is a rare autosomal recessive disorder characterized by stunted growth, sun-sensitive erythema and immunodeficiency. Chromosomal abnormalities are often observed. Patients with BS are highly predisposed to cancers. The causative gene for BS has been identified as BLM. The former encodes a protein, which is a homologue of the RecQ DNA helicase family, a family which includes helicases such as...

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Share to Complementarity Determining Regions
Share to DNA Helicases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Rearrangement, B-Lymphocyte

Share to Genes, Immunoglobulin

Share to Hematopoietic Stem Cells

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Source

Open in PubMed Open full text

Identifiers

PMID: 10540192
DOI: 10.1046/j.1365-2249.1999.01060.x
PMCID: PMC1905425

Genes

BLM
WRN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of the BLM gene in human haematopoietic cells.PMID 10540192Read ↗

Role of the Bloom's syndrome helicase in maintenance of genome stability.Semantic proximity Read ↗

Immunodeficiency in Bloom's Syndrome.Semantic proximity Read ↗

Clinical features of Bloom syndrome and function of the causative gene, BLM helicaseSemantic proximity Read ↗

Bloom syndrome and the underlying causes of genetic instability.Semantic proximity Read ↗

[Bloom syndrome].Semantic proximity Read ↗

The function of RecQ helicase gene family (especially BLM) in DNA recombination and joining.Semantic proximity Read ↗

A case of Bloom syndrome manifesting with therapy-related myelodysplastic syndromes harboring a novel BLM gene variant.Semantic proximity Read ↗

Characterization of a new BLM mutation associated with a topoisomerase II alpha defect in a patient with Bloom's syndrome.Semantic proximity Read ↗

The Bloom's syndrome gene product is homologous to RecQ helicases.Semantic proximity Read ↗

A novel frameshift mutation in BLM gene associated with high sister chromatid exchanges (SCE) in heterozygous family members.Semantic proximity Read ↗

Genomic instability and cancer: lessons from analysis of Bloom's syndrome.Semantic proximity Read ↗

Functional Interaction of p53 and BLM DNA Helicase in ApoptosisSemantic proximity Read ↗

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