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Combined spectral karyotyping and DAPI banding analysis of chromosome abnormalities in myelodysplastic syndrome

1 Dec 1999

Abstract excerpt

Spectral karyotyping (SKY) is a new molecular cytogenetic technique that allows simultaneous visualization of each chromosome in a different color. We have used SKY for comprehensive analysis of 20 myelodysplastic syndromes (MDSs) (13 primary MDSs, 3 therapy-related MDSs, and 4 acute leukemias developed from MDS, including 1 cell line established from a secondary leukemia), previously analyzed by G-banding. To...

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PMID: 10534769
DOI: 10.1002/(sici)1098-2264(199912)26:4<336::aid-gcc8>3.0.co;2-h

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