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Article

Emergence of <i>Anaplasma marginale</i> Antigenic Variants during Persistent Rickettsemia

1 Nov 1999

Abstract excerpt

Anaplasma marginale is an ehrlichial pathogen of cattle, in the order Rickettsiales, that establishes persistent cyclic rickettsemia in the infected host. Within each rickettsemic cycle, A. marginale expressing antigenically variant major surface protein 2 (MSP2) emerge. By cloning 17 full-length msp2 transcripts expressed during cyclic rickettsemia, we determined that emergent variants have a single, central...

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PMID: 10531237
DOI: 10.1128/iai.67.11.5834-5840.1999

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Emergence of <i>Anaplasma marginale</i> Antigenic Variants during Persistent RickettsemiaPMID 10531237Read ↗

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