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Article

Control ofLeishmania infantumInfection Is Associated with CD8+and Gamma Interferon- and Interleukin-5-Producing CD4+Antigen-Specific T Cells

1 Nov 1999

Abstract excerpt

Visceral leishmaniasis is a severe and lethal disease caused by the protozoan parasites of the genus Leishmania. In areas where leishmaniasis is endemic, most infected individuals control the infection and remain asymptomatic; chemotherapy of visceral leishmaniasis restores some immunity which protects against relapses. In the present study, Leishmania-specific T-cell clones were established from six asymptomatic...

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PMID: 10531200
DOI: 10.1128/iai.67.11.5559-5566.1999

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