Article
Presence and expression of a novel variant form of ST2 gene product in human leukemic cell line UT-7/GM.
Biochemical and biophysical research communications - 14 Oct 1999
Tominaga S i, Kuroiwa K, Tago K, Iwahana H, Yanagisawa K, Komatsu N
Abstract excerpt
A novel variant cDNA from the human ST2 gene other than ST2 or ST2L was identified and tentatively named ST2V. Alternative splicing inserts a new exon which leads to a change in the C-terminal portion of ST2, causing it to gain a hydrophobic tail instead of losing the third immunoglobulin-like domain. ST2V is expressed in human leukemic cell line UT-7 and its sublines UT-7/GM, UT-7/EPO, and UT-7/TPO, in addition...
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