Article
The reduced expression of 6Ckine in the plt mouse results from the deletion of one of two 6Ckine genes.
The Journal of experimental medicine - 18 Oct 1999
Vassileva G, Soto H, Zlotnik A, Nakano H, Kakiuchi T, Hedrick J A, Lira S A
Abstract excerpt
6Ckine is an unusual chemokine capable of attracting naive T lymphocytes in vitro. It has been recently reported that lack of 6Ckine expression in lymphoid organs is a prominent characteristic of mice homozygous for the paucity of lymph node T cell (plt) mutation. These mice show reduced numbers of T cells in lymph nodes, Peyer's patches, and the white pulp of the spleen. The genetic reason for the lack of 6Ckine...
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