Article
A clinical study of a large inbred kindred with pure familial spastic paraplegia.
Brain & development - 1 Oct 1999
El-Shanti H E, Daoud A S, Batieha A
Abstract excerpt
BACKGROUND AND OBJECTIVES: Spastic paraplegia, an uncommon neurodegenerative disorder with phenotypic and genotypic heterogeneity, is mainly characterized by progressive weakness and spasticity of the lower limbs. We here present a large inbred family with pure familial spastic paraplegia outlining the clinical picture, the age at onset and the possible mode of inheritance. METHODS: This family was ascertained...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.