Article
Marked differences in the frequency of microsatellite instability in gastric cancer from different countries.
The American journal of gastroenterology - 1 Oct 1999
Sepulveda A R, Santos A C, Yamaoka Y, Wu L, Gutierrez O, Kim J G, Graham D Y
Abstract excerpt
OBJECTIVE: Previous studies have reported variable rates of microsatellite instability (MSI) in gastric cancer. We investigated the frequency of MSI in invasive gastric carcinoma of patients from three geographic regions. METHODS: Genomic DNA from gastric cancer and nontumor tissue from 22 Korean, 20 Colombian, and 26 U.S. patients was amplified with five microsatellite markers. RESULTS: MSI was more frequently...
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