Article
A nucleotide deletion in exon 4 is responsible for an HLA-A null allele (A*0105N).
Tissue antigens - 1 Sept 1999
Poli F, Bianchi P, Scalamogna M, Crespiatico L, Ghidoli N, Puglisi G, Sirchia G
Abstract excerpt
We report herein the identification of a new HLA-A null allele. This allele, A*0105N, was detected during histocompatibility testing of a cord blood donor and the respective mother. Serologic typing results contrasted those obtained with DNA typing that alone showed the presence of HLA-A*01. ThisA*0105N was due to a nucleotide deletion in exon 4 that altered the reading frame, causing a premature termination.
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