Article
Effect of acetylation (O-factor 5) on the polyclonal antibody response to Salmonella typhimurium O-antigen.
FEMS immunology and medical microbiology - 1 Oct 1999
Kim M L, Slauch J M
Abstract excerpt
Antibodies directed against lipopolysaccharide (LPS) O-antigen are often critical in the immune response to Gram-negative pathogens. Mice were orally immunized with isogenic strains of Salmonella typhimurium that differ only in a minor modification of O-antigen, namely acetylation, mediated by the oafA locus. To specifically examine the effect of acetylation on the antibody response to O-antigen, antibody titers...
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