Article
Polymorphisms XbaI (rs693) and EcoRI (rs1042031) of the ApoB gene are associated with carotid plaques but not with carotid intima-media thickness in patients with diabetes mellitus type 2.
VASA. Zeitschrift fur Gefasskrankheiten - 1 May 2014
Nikolajevic Starcevic Jovana, Santl Letonja Marija, Praznikar Zala J, Makuc Jana, Vujkovac Andreja C, Petrovic Daniel
Abstract excerpt
BACKGROUND: Apolipoprotein B is a key structural component of all the atherogenic lipoproteins (LDL, VLDL and IDL). Genetic variations of the ApoB gene may affect plasma ApoB and lipid levels, thus influencing atherogenesis. The present study was designed to investigate the association of polymorphisms XbaI (rs693) and EcoRI (rs1042031) of the ApoB gene with plasma ApoB level, lipid levels and the different...
Topics
- Aged
- Apolipoproteins B
- Carotid Arteries
- Carotid Artery Diseases
- Carotid Intima-Media Thickness
- Case-Control Studies
- Chi-Square Distribution