Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of hepatic lipase in lipoprotein metabolism.

Clinica chimica acta; international journal of clinical chemistry - 1 Aug 1999

Connelly P W

Abstract excerpt

Hepatic lipase (HL) is one of two major lipases released from the vascular bed by intravenous injection of heparin. HL hydrolyzes phospholipids and triglycerides of plasma lipoproteins and is a member of a lipase superfamily that includes lipoprotein lipase and pancreatic lipase. The enzyme can be divided into an NH2-terminal domain containing the catalytic site joined by a short spanning region to a smaller...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Coronary Disease
Share to Evolution, Molecular
Share to Lipase

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Lipoproteins

Share to Mice, Knockout

Share to Protein Conformation

Share to Substrate Specificity

Source

Identifiers

PMID: 10511296
DOI: 10.1016/s0009-8981(99)00105-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of hepatic lipase in lipoprotein metabolism.PMID 10511296Read ↗

Hepatic lipase deficiency.Semantic proximity Read ↗

Hepatic lipase, high density lipoproteins, and hypertriglyceridemia.Semantic proximity Read ↗

Lipoprotein lipase: physiology, biochemistry, and molecular biology.Semantic proximity Read ↗

Structure, function and role of lipoprotein lipase in lipoprotein metabolism.Semantic proximity Read ↗

Update on the role of endothelial lipase in high-density lipoprotein metabolism, reverse cholesterol transport, and atherosclerosis.Semantic proximity Read ↗

Lipoprotein metabolism in subjects with hepatic lipase deficiency.Semantic proximity Read ↗

Hepatic lipase and dyslipidemia: interactions among genetic variants, obesity, gender, and diet.Semantic proximity Read ↗

Heterozygous hepatic lipase deficiency, due to two missense mutations R186H and L334F, in the HL gene.Semantic proximity Read ↗

Lipoprotein lipase: recent contributions from molecular biology.Semantic proximity Read ↗

A compound heterozygote for hepatic lipase gene mutations Leu334-->Phe and Thr383-->Met: correlation between hepatic lipase activity and phenotypic expression.Semantic proximity Read ↗

Endothelial-derived lipoprotein lipase is bound to postprandial triglyceride-rich lipoproteins and mediates their hepatic clearance in vivo.Semantic proximity Read ↗

The effect of hepatic lipase on coronary artery disease in humans is influenced by the underlying lipoprotein phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.