Article
Exclusion of dominant mutations within the FTDP-17 locus on chromosome 17 for Parkinson's disease.
Neuroscience letters - 10 Sept 1999
Zareparsi S, Wirdefeldt K, Burgess C E, Nutt J, Kramer P, Schalling M, Payami H
Abstract excerpt
Parkinson's disease (PD) is a prevalent movement disorder, and 10-30% of PD is familial. Several neurodegenerative disorders which are collectively called frontotemporal dementia and parkinsonism have been mapped to chromosome 17q and mutations in tau have been identified. The clinical and pathological overlap suggests that these related conditions may be due to mutations in tau. We examined linkage to the...
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