Emergence of lamivudine resistance hepatitis B virus mutations in pregnant women infected with HBV and HIV receiving antiretroviral prophylaxis for the prevention of mother-to-infant transmission in Malawi.

doi:10.1002/jmv.23365

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Article

Emergence of lamivudine resistance hepatitis B virus mutations in pregnant women infected with HBV and HIV receiving antiretroviral prophylaxis for the prevention of mother-to-infant transmission in Malawi.

Journal of medical virology - 1 Oct 2012

Galluzzo Clementina, Liotta Giuseppe, Andreotti Mauro, Luhanga Richard, Jere Haswell, Mancinelli Sandro, Maulidi Martin, Sagno Jean-Baptiste, Pirillo Maria, Erba Fulvio, Amici Roberta, Ceffa Susanna, Marazzi Maria Cristina, Vella Stefano, Palombi Leonardo, Giuliano Marina

Abstract excerpt

HIV/HBV co-infection is highly prevalent in sub-Saharan Africa. The aim of this study was to determine if the use of triple combination lamivudine-containing prophylaxis for the prevention of mother-to-infant HIV transmission was associated with the emergence of lamivudine HBV mutations. The study included 21 pregnant co-infected women in Malawi who received either zidovudine or stavudine plus lamivudine and...

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PMID: 22930502
DOI: 10.1002/jmv.23365

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