Article
Paroxysmal nocturnal hemoglobinuria cells in patients with bone marrow failure syndromes.
Annals of internal medicine - 21 Sept 1999
Dunn D E, Tanawattanacharoen P, Boccuni P, Nagakura S, Green S W, Kirby M R, Kumar M S, Rosenfeld S, Young N S
Abstract excerpt
BACKGROUND: Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired hematopoietic stem-cell disorder in which the affected cells are deficient in glycosylphosphatidylinositol (GPI)-anchored proteins. Paroxysmal nocturnal hemoglobinuria is frequently associated with aplastic anemia, although the basis of this relation is unknown. OBJECTIVE: To assess the PNH status of patients with diverse marrow failure...
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