Article
Detection of paroxysmal nocturnal hemoglobinuria clones in patients with myelodysplastic syndromes and related bone marrow diseases, with emphasis on diagnostic pitfalls and caveats.
Haematologica - 1 Jan 2009
Wang Sa A, Pozdnyakova Olga, Jorgensen Jeffrey L, Medeiros L Jeffrey, Stachurski Dariusz, Anderson Mary, Raza Azra, Woda Bruce A
Abstract excerpt
BACKGROUND: The presence of paroxysmal nocturnal hemoglobinuria clones in the setting of aplastic anemia or myelodysplastic syndrome has been shown to have prognostic and therapeutic implications. However, the status of paroxysmal nocturnal hemoglobinuria clones in various categories of myelodysplastic syndrome and in other bone marrow disorders is not well-studied. DESIGN AND METHODS: By using multiparameter...
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