The haemochromatosis gene: a co-factor for chronic liver diseases?

Abstract excerpt

There is increasing evidence that hepatotoxins, such as alcohol and the hepatitis viruses, act as co-factors in causing hepatic fibrosis and cirrhosis. For example, alcohol aggravates the hepatic damage produced by iron in hereditary haemochromatosis. We present evidence that the reverse is also true, that is, that iron loading of mild to moderate degree due to heterozygosity or homozygosity for the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Chronic Disease
• Share to Genetic Predisposition to Disease
• Share to Hemochromatosis