Article
[Genetic factors which regulate alcohol drinking behavior and their effects on health status].
Nihon eiseigaku zasshi. Japanese journal of hygiene - 1 Jul 1999
Takeshita T
Abstract excerpt
High alcohol sensitivity common among Orientals is mainly due to genetic polymorphism in the low K(m) aldehyde dehydrogenase (ALDH2) gene. The relation of the ALDH2 genotype to alcohol sensitivity and drinking behavior was investigated in a Japanese occupational population. The frequency of alcohol-associated symptoms generally increased in the order of the typical homozygote, heterozygote, and atypical...
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