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Article

Genetic association of the catalase gene (CAT) with vitiligo susceptibility.

Pigment cell research - 1 Feb 2002

Casp Courtney B, She Jin-Xiong, McCormack Wayne T

Abstract excerpt

Vitiligo susceptibility is a complex genetic trait that may involve genes important for melanin biosynthesis, response to oxidative stress, and/or regulation of autoimmunity, as well as environmental factors. We report here case-control and family-based association studies for the catalase gene (CAT) in vitiligo patients. The CAT gene was selected as a candidate gene because of the reduction of catalase enzyme...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11837458
DOI: 10.1034/j.1600-0749.2002.00057.x

Genes

CAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Genetic association of the catalase gene (CAT) with vitiligo susceptibility.PMID 11837458Read ↗

Analysis of allelic variants in the catalase gene in patients with the skin depigmenting disorder vitiligo.Semantic proximity Read ↗

No association between catalase (CAT) gene polymorphisms and susceptibility to vitiligo in a Turkish population.Semantic proximity Read ↗

Association study between catalase gene polymorphisms and the susceptibility to vitiligo in Korean population.Semantic proximity Read ↗

The catalase gene promoter and 5'-untranslated region variants lead to altered gene expression and enzyme activity in vitiligo.Semantic proximity Read ↗

Association of the 389 C/T polymorphism of the catalase gene with susceptibility to vitiligo: a meta-analysis.Semantic proximity Read ↗

The polymorphism of catalase T/C codon 389 in exon 9 and vitiligo susceptibility: a meta-analysis.Semantic proximity Read ↗

Promoter variant in the catalase gene is associated with vitiligo in Chinese people.Semantic proximity Read ↗

Evaluation of CAT Variants A-89T, C389T, and C419T in Patients with Vitiligo in the Saudi Population.Semantic proximity Read ↗

Lack of association between the 389C>T polymorphism (rs769217) in the catalase (CAT) gene and the risk of vitiligo: an update by meta-analysis.Semantic proximity Read ↗

Lack of association between catalase gene polymorphism (T/C exon 9) and susceptibility to vitiligo in a Turkish population.Semantic proximity Read ↗

Vitiligo susceptibility and catalase gene polymorphisms in Sicilian population.Semantic proximity Read ↗

Computer simulation of heterogeneous single nucleotide polymorphisms in the catalase gene indicates structural changes in the enzyme active site, NADPH-binding and tetramerization domains: a genetic predisposition for an altered catalase in patients with vitiligo?Semantic proximity Read ↗

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