Article
Structural basis for selective inhibition of Src family kinases by PP1.
Chemistry & biology - 1 Sept 1999
Liu Y, Bishop A, Witucki L, Kraybill B, Shimizu E, Tsien J, Ubersax J, Blethrow J, Morgan D O, Shokat K M
Abstract excerpt
BACKGROUND: Small-molecule inhibitors that can target individual kinases are powerful tools for use in signal transduction research. It is difficult to find such compounds because of the enormous number of protein kinases and the highly conserved nature of their catalytic domains. Recently, a nov...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
