Article
Hansenula polymorpha Pex1p and Pex6p are peroxisome-associated AAA proteins that functionally and physically interact.
Yeast (Chichester, England) - 1 Aug 1999
Kiel J A, Hilbrands R E, van der Klei I J, Rasmussen S W, Salomons F A, van der Heide M, Faber K N, Cregg J M, Veenhuis M
Abstract excerpt
We have cloned the Hansenula polymorpha PEX1 and PEX6 genes by functional complementation of the corresponding peroxisome-deficient (pex) mutants. The gene products, HpPex1p and HpPex6p, are ATPases which both belong to the AAA protein family. Cells deleted for either gene (Deltapex1 or Deltapex6) were characterized by the presence of small peroxisomal remnants which contained peroxisomal membrane proteins and...
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