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Article

A pilot study on risperidone metabolism: the role of cytochromes P450 2D6 and 3A.

The Journal of clinical psychiatry - 1 Jul 1999

Bork J A, Rogers T, Wedlund P J, de Leon J

Abstract excerpt

BACKGROUND: The limited available information on plasma risperidone levels shows a stable relationship between daily doses of risperidone and total plasma concentration (risperidone plus its active metabolite 9-hydroxyrisperidone). The ratio between risperidone and 9-hydroxyrisperidone characterizes cytochrome P450 2D6 (CYP2D6) status. According to the manufacturer, the CYP2D6 genotype or drugs that influence...

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Source

Identifiers

PMID: 10453802

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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