Article
The effect of bu shen sheng xue fang on beta-thalassemia at gene level.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan - 1 Dec 1998
Wu Z, Jiang B, Cui J, Ji X, Huang X, Cai H, Chen P, Wang R, Huang Y
Abstract excerpt
Isoelectrofocusing electrophoresis, PCR-SSCP analysis with DNA direct sequencing and RT-PCR were used to analyze the constituents of hemoglobin, determine the pattern of globin gene mutation, and detect its mRNA transcription extent. The results indicated that Bu Shen Sheng Xue Fang (BSSXF) significantly increased the contents of hemoglobin (Hb) and fetal hemoglobin (HbF), and the chain ratio in patients with...
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