Genetic pathways in colorectal and other cancers.

doi:10.1016/s0959-8049(98)00431-6

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Article

Genetic pathways in colorectal and other cancers.

European journal of cancer (Oxford, England : 1990) - 1 Mar 1999

Ilyas M, Straub J, Tomlinson I P, Bodmer W F

Abstract excerpt

Cells from cancers show aberrant behaviour such as unrestrained growth, invasion into adjacent tissue and metastasis. All these features of cancer cell behaviour can be explained in terms of genetic changes and the functional impact of these changes. In this review, colorectal cancer (CRC) is examined as a classical example of multistep carcinogenesis. First there is an overview which shows that cancers develop...

Topics

Colorectal Neoplasms
Global Health
Humans
Mutation

Source

Open in PubMed

Identifiers

PMID: 10448282
DOI: 10.1016/s0959-8049(98)00431-6

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