Article
Heterozygosity excess at the cattle DRB locus revealed by large scale genotyping of two closely linked microsatellites.
Animal genetics - 1 Jun 1999
van Haeringen W A, Gwakisa P S, Mikko S, Eythorsdottir E, Holm L E, Olsaker I, Outteridge P, Andersson L
Abstract excerpt
A method for MHC DRB typing in cattle based on two closely linked and highly polymorphic microsatellites is described. The two microsatellites DRBP1ms and DRB3ms are located in intron 2 of the corresponding DRB gene. The very strong linkage disequilibrium between the two loci made it possible to establish DRB microsatellite haplotypes. The typing results with this method on reference samples followed closely that...
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