Article
[The risk factors for the development of multiple sclerosis in the Moscow population. II. The combination of exogenous and hereditary factors].
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova - 1 Jan 1999
Gusev E I, Boĭko A N, Demina T L, Sudomoina M A, Alekseev A P, Boldyreva M N, Trofimov D Iu, Favorova O O
Abstract excerpt
Simultaneous study of both external and hereditary risk factors of the development of multiple sclerosis (MS) was carried out in Moscow population. As a result of the genotyping of HLA-DR locus on the chromosome 6, there were found markers of the predisposition to MS: by HLA-DR: DR2(15) way, especially, in homozygous heredity and in the absence of such specificity--alleles of DR3 group. The data were confirmed...
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