Article
[Genetic aspects in multiple sclerosis. II: HLA system].
Arquivos de neuro-psiquiatria - 1 Sept 1996
De Rezende P A, Arruda W O
Abstract excerpt
Review of studies about HLA antigens and multiple sclerosis (MS). The HLA system, in special class II antigens, subregions DR and DQ, is probably involved in the immunopathogenesis of MS. Haplotype DRB1*1501.DQA1*0102.DQB1*0602, corresponding to phenotype DR2.Dw2.DQ6, is positively associated with MS in several caucasoid populations. Clinical heterogeneity of MS, as well as different diagnostic criteria adopted...
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