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Article

Biosynthesis of Classical Swine Fever Virus Nonstructural Proteins

27 Jan 2011

Abstract excerpt

Proteolytic processing of polyproteins is considered a crucial step in the life cycle of most positive-strand RNA viruses. An enhancement of NS2-3 processing has been described as a major difference between the noncytopathogenic (non-CP) and the cytopathogenic (CP) biotypes of pestiviruses. The effects of accelerated versus delayed NS2-3 processing on the maturation of the other nonstructural proteins (NSP) have...

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Identifiers

PMID: 21270154
DOI: 10.1128/jvi.02206-10

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