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Article

Paroxetine pharmacokinetics in depressed children and adolescents.

Journal of the American Academy of Child and Adolescent Psychiatry - 1 Aug 1999

Findling R L, Reed M D, Myers C, O'Riordan M A, Fiala S, Branicky L, Waldorf B, Blumer J L

Abstract excerpt

OBJECTIVE: To describe the pharmacokinetics and safety of paroxetine in children and adolescents and to explore the role of genetic polymorphisms in paroxetine pharmacokinetics. METHOD: Thirty depressed youths were enrolled. Samples for phenotyping with respect to cytochrome P450 2D6 (CYP2D6) and catechol-O-methyltransferase were collected. A single 10-mg dose of paroxetine was then administered followed by 5...

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Source

Identifiers

PMID: 10434486
DOI: 10.1097/00004583-199908000-00010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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