Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The dynamics of human cytomegalovirus replication in vivo.

The Journal of experimental medicine - 19 Jul 1999

Emery V C, Cope A V, Bowen E F, Gor D, Griffiths P D

Abstract excerpt

Cytomegalovirus (CMV) is generally described as a slowly replicating virus. During studies of immunocompromised patients, we observed rapid changes in the quantity of CMV DNA present in serial blood samples by quantitative-competitive polymerase chain reaction commensurate with a doubling time of <2 d. To further investigate the dynamics of replication in vivo, patients in three distinct situations were studied...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus
Share to Cytomegalovirus Infections
Share to DNA Replication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Microbial

Share to Ganciclovir

Share to Genes, Viral

Share to Phosphotransferases (Alcohol Group Acceptor)

Share to Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 10432281
DOI: 10.1084/jem.190.2.177
PMCID: PMC2195570

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The dynamics of human cytomegalovirus replication in vivo.PMID 10432281Read ↗

Prediction of cytomegalovirus load and resistance patterns after antiviral chemotherapy.Semantic proximity Read ↗

The interplay between host and viral factors in shaping the outcome of cytomegalovirus infection.Semantic proximity Read ↗

Novel decay dynamics revealed for virus-mediated drug activation in cytomegalovirus infection.Semantic proximity Read ↗

Cytomegalovirus latency—the sum of subtletiesSemantic proximity Read ↗

Latency versus persistence or intermittent recurrences: evidence for a latent state of murine cytomegalovirus in the lungsSemantic proximity Read ↗

Preemptive CD8 T-Cell Immunotherapy of Acute Cytomegalovirus Infection Prevents Lethal Disease, Limits the Burden of Latent Viral Genomes, and Reduces the Risk of Virus RecurrenceSemantic proximity Read ↗

Early Kinetics of Plasma Cytomegalovirus DNA Load in Allogeneic Stem Cell Transplant Recipients in the Era of Highly Sensitive Real-Time PCR Assays: Does It Have Any Clinical Value?Semantic proximity Read ↗

Quantitative Analysis of Latent Human CytomegalovirusSemantic proximity Read ↗

Detection of ganciclovir resistance mutations quantitation of cytomegalovirus (CMV) DNA in leukocytes of patients with fatal disseminated CMV disease.Semantic proximity Read ↗

Cytomegalovirus (CMV) resistance to antivirals.Semantic proximity Read ↗

Cidofovir, a New Agent with Potent Anti-Herpesvirus ActivitySemantic proximity Read ↗

Growth phenotypes of cytomegalovirus isolates do not correlate with glycoprotein B, major immediate early genotypes or antiviral sensitivity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.