Article
ATP-regulation of cytochrome oxidase in yeast mitochondria: role of subunit VIa.
European journal of biochemistry - 1 Jul 1999
Beauvoit B, Bunoust O, Guérin B, Rigoulet M
Abstract excerpt
The role of the nuclear-encoded subunit VIa in the regulation of cytochrome oxidase by ATP was investigated in isolated yeast mitochondria. As the subunit VIa-null strain possesses a fully active and assembled cytochrome oxidase, multiple ATP-regulating sites were characterized with respect to their location and their kinetic effect: (a) intra-mitochondrial ATP inhibited the complex IV activity of the null...
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