Article
Involvement of gene products in bacterial evolution.
Annals of the New York Academy of Sciences - 18 May 1999
Arber W
Abstract excerpt
Three strategies of different quality contribute in parallel to the natural formation of genetic variants in bacteria: (1) small local alterations of DNA sequences; (2) recombinational reshuffling of segments of the genome; and (3) acquisition of DNA sequences by horizontal gene transfer. Key enzymes involved in these processes often act as variation generators by making use of structural flexibilities of...
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