Article
Evidence of a major locus for lipoprotein lipase (LPL) activity in addition to a pleiotropic locus for both LPL and fasting insulin: results from the HERITAGE Family Study.
Atherosclerosis - 1 Jun 1999
Hong Y, Rice T, Després J P, Gagnon J, Nadeau A, Bergeron J, Pérusse L, Bouchard C, Leon A S, Skinner J S, Wilmore J H, Rao D C
Abstract excerpt
A major gene hypothesis for heparin releasable plasma lipoprotein lipase (PH-LPL) activity was assessed using segregation analyses of data on 495 members in 98 normolipidemic sedentary families of Caucasian descent who participated in the HERITAGE Family Study. Segregation analyses were performed on PH-LPL adjusted for age, and on PH-LPL activity adjusted for age and fasting insulin. Prior to adjustment for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.