Article
Familial aggregation of lupus and autoimmunity in an unusual multiplex pedigree.
The Journal of rheumatology - 1 Jul 1999
Sestak A L, Shaver T S, Moser K L, Neas B R, Harley J B
Abstract excerpt
OBJECTIVE: To evaluate an unusual pedigree with 8 members diagnosed with systemic lupus erythematosus (SLE) METHODS: Pedigree members were evaluated through questionnaires, interviews, and medical records. Sixty members contributed serum samples for autoantibody analysis. RESULTS: The 8 affected females shared several disease features, including arthritis (8/8), antinuclear antibodies (ANA) (8/8), pleuritis...
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