Article
Familial lupus erythematosus. Clinical and immunologic features of 125 multiplex families.
Medicine - 1 May 2001
Michel M, Johanet C, Meyer O, Francès C, Wittke F, Michel C, Arfi S, Tournier-Lasserve E, Piette J C
Abstract excerpt
Evidence for a genetic susceptibility to systemic lupus erythematosus (SLE) in humans is based on the high concordance rate observed in identical twins and on the relatively high incidence of familial cases. Although recent genetic studies have lead to significant advances in the identification of new susceptibility genes in SLE, no large clinico-pathologic study of familial SLE has been reported to date. In the...
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